Had a Windows 7 PC with AnyConnect 4.5 and Palo Alto GlobalProtect 4.1. Both VPNs use split tunnel. I was able to connect to both VPNs simultaneously and do my work. After connecting to Global Protect, I see this in netstat -rn:
10.69.0.0 255.255.0.0 On-link 10.69.69.206 1
I then connect to AnyConnect which adds this route:
10.0.0.0 255.0.0.0 10.11.12.1 10.11.12.225 2
No problem since the 10.69.0.0/16 route is still there and overrides the 10.0.0.0/8. All so good.
However, I’ve been forced to switch to a Windows 10 PC and now having problems, specifically with AnyConnect removing the GlobalProtect’s routes. Not sure if it’s specifically because of the 10.0.0.0/8 overlap, but when I connect to AnyConnect, the 10.69.0.0/16 route disappears from the route table.
SOLVED!!!
The new Windows 10 laptop shipped with AnyConnect 4.3. I had custom upgraded the Windows 7 laptop to AnyConnect 4.5 since I knew 4.3 was end of life. Repeated the upgrade to 4.5.05030 and works fine now.
Too lazy to read through the AnyConnect bugs but I’m sure I was hitting one. Have been nagging them to get on AnyConnect 4.4 or 4.5 and it’s fallen on deaf ears.